Launching September 2026

Anti-Aging

Get Personalized Anti-Aging Care

Aging skin is a natural part of life, but factors like sun exposure, lifestyle, and genetics can accelerate the appearance of fine lines, uneven tone, dryness, and loss of firmness. While no treatment can stop the aging process, evidence-based skincare can help improve your skin’s appearance and support healthier-looking skin over time.

At APNS, our providers take the time to understand your skin concerns, goals, and medical history before recommending a personalized treatment plan. Whether you’re looking to address early signs of aging or maintain healthier skin for years to come, we offer convenient telehealth consultations with transparent pricing, no membership fees, and no insurance required.

About Atrophic Skin Disorder / Aging Skin

What Is Atrophic Skin Disorder?

Atrophic skin disorder refers to skin that has become thinner, more fragile, less elastic, and more prone to wrinkles, bruising, tearing, dryness, and irritation. In everyday language, this is often called aging skin.

Aging skin may appear as:

  • Fine lines
  • Wrinkles
  • Thin or fragile skin
  • Crepey texture
  • Brown spots or “age spots”
  • Uneven skin tone
  • Rough texture
  • Enlarged pores
  • Skin laxity or sagging
  • Easy bruising
  • Slow wound healing

Disease Statistics

Atrophic skin disorder, often referred to as aging skin, skin thinning, or photoaging, is extremely common and affects nearly everyone to some degree over time. Skin aging is caused by a combination of natural aging and environmental damage, especially ultraviolet (UV) radiation from the sun.

  • Photoaging, or premature skin aging from sun exposure, is responsible for a large portion of visible aging changes, including wrinkles, brown spots, rough texture, and skin laxity.
  • The Skin Cancer Foundation reports that photoaging is responsible for about 90% of visible changes to the skin.
  • A 2025 American Academy of Dermatology survey found that half of Americans worry about premature skin aging, but only about half use sunscreen regularly.
  • The same AAD survey found that 4 in 10 adults report wrinkles or dark spots they believe are from sun exposure.

Table of Contents

Table of Contents

What Causes Aging Skin?

Aging skin is usually caused by a combination of intrinsic aging and extrinsic aging.

Intrinsic Aging

Intrinsic aging is the natural aging process. Over time, the skin gradually produces less collagen, elastin, and natural moisturizing factors. This leads to thinner, drier, less elastic skin.

Extrinsic Aging

Extrinsic aging is caused by outside factors. The most important cause is sun exposure.

Common contributors include:

  • UV radiation from sunlight
  • Tanning beds
  • Smoking
  • Pollution
  • Poor sleep
  • Chronic inflammation
  • Repeated facial expressions
  • Poor nutrition
  • Certain medications, such as long-term topical or oral steroids
  • Hormonal changes, especially after menopause

How Is Aging Skin Treated?

Treatment depends on the patient’s goals, skin type, severity of skin aging, and tolerance for irritation or procedures.

Lifestyle Changes

Lifestyle treatment is the foundation of aging skin care.

Important steps include:

  • Use broad-spectrum sunscreen SPF 30 or higher every day
  • Avoid tanning beds
  • Wear hats, sunglasses, and sun-protective clothing
  • Stop smoking
  • Use a gentle cleanser
  • Moisturize daily
  • Avoid harsh scrubs or over-exfoliation
  • Maintain good sleep habits
  • Eat a balanced diet rich in fruits, vegetables, protein, and healthy fats
  • Treat dryness and irritation early

Medications

Prescription retinoids such as tretinoin and tazarotene have the strongest evidence for improving wrinkles, collagen production, skin texture, and photoaging.

Retinoids (Collagen Builders)

  • Adapalene
  • Retinaldehyde (Retinal)
  • Tretinoin
  • Tazarotene

Antioxidants / Barrier Support

  • Vitamin C
  • Niacinamide (Nicotinamide)

Pigmentation Treatments

  • Azelaic Acid
  • Hydroquinone
  • Cysteamine

Hydration / Skin Barrier Support

  • Hyaluronic Acid
  • Ceramides

Clinical Pearl

Niacinamide is one of the best ingredients to pair with tretinoin or tazarotene because it can help reduce irritation while improving skin barrier function.

For more detailed information about the various medications commonly used to treat aging skin, including dosing, side effects, and what to expect, visit our Anti-Aging Medication Guide.

Anti-Aging Effectiveness Ranking

Not sure which anti-aging treatment is right for you? Use this table as a general guide. Your APNS provider will recommend the most appropriate treatment based on your skin type, goals, and medical history.

TreatmentCollagen StimulationFine Lines & WrinklesPigmentationTexture ImprovementTolerabilityOverall Anti-Aging Strength
Tazarotene★★★★★★★★★★★★★★★★★★★★★★☆☆☆★★★★★
Tretinoin★★★★★★★★★★★★★★★★★★★★★★★☆☆★★★★★
Retinaldehyde (Retinal)★★★★☆★★★★☆★★★★☆★★★★☆★★★★☆★★★★☆
Adapalene★★★☆☆★★★☆☆★★☆☆☆★★★☆☆★★★★☆★★★☆☆
Vitamin C★★★☆☆★★☆☆☆★★★★★★★☆☆☆★★★★☆★★★★☆
Hydroquinone☆☆☆☆☆☆☆☆☆☆★★★★★★★☆☆☆★★★☆☆★★★☆☆
Cysteamine☆☆☆☆☆☆☆☆☆☆★★★★☆★★☆☆☆★★★☆☆★★★☆☆
Azelaic Acid★★☆☆☆★★☆☆☆★★★★☆★★☆☆☆★★★★★★★★☆☆
Niacinamide★★☆☆☆★★☆☆☆★★★☆☆★★☆☆☆★★★★★★★★☆☆
Hyaluronic Acid☆☆☆☆☆★★☆☆☆*☆☆☆☆☆★★☆☆☆★★★★★★★☆☆☆
Ceramides☆☆☆☆☆★☆☆☆☆☆☆☆☆☆★★☆☆☆★★★★★★★☆☆☆

Note: *Primarily through hydration and plumping effects rather than true collagen stimulation.

Interpretation of the Rankings

Tier 1 – Prescription Retinoids (Gold Standard)

Tazarotene and Tretinoin
These are the only topical anti-aging treatments with extensive evidence demonstrating:
  • Increased collagen production
  • Reduced collagen breakdown
  • Improvement in fine lines
  • Improvement in wrinkles
  • Improvement in texture
  • Improvement in pigmentation
  • Partial reversal of photoaging
If a patient’s goal is to actually change the biology of aging skin, these are generally the strongest options.

Tier 2 – Advanced Non-Prescription Retinoids

Retinaldehyde (Retinal)
Retinaldehyde sits between retinol and prescription retinoids. Advantages:
  • Less irritating than tretinoin
  • Better tolerated than tazarotene
  • Strong anti-aging evidence
  • Available without a prescription
Many dermatologists consider retinaldehyde the best non-prescription anti-aging ingredient currently available.

Tier 3 – Supporting Anti-Aging Ingredients

Vitamin C
Niacinamide
Azelaic Acid
These ingredients do not stimulate collagen to the same degree as retinoids but can provide substantial benefits. Vitamin C:
  • Antioxidant protection
  • Brightening
  • Pigmentation improvement
  • Prevention of future photoaging
Niacinamide:
  • Improves skin barrier
  • Reduces redness
  • Improves hydration
  • Helps tolerate retinoids
Azelaic Acid:
  • Improves pigmentation
  • Helps rosacea
  • Reduces redness
  • Useful for sensitive skin

Tier 4 – Pigmentation Specialists

Hydroquinone
Cysteamine
These treatments are primarily chosen when:
  • Age spots
  • Sun spots
  • Melasma
  • Uneven pigmentation
are the primary concern. They do not meaningfully improve wrinkles or stimulate collagen.

Tier 5 – Barrier and Hydration Support

Hyaluronic Acid
Ceramides
These ingredients improve:
  • Hydration
  • Skin barrier function
  • Dryness
  • Irritation
They are often used alongside retinoids. They can make skin appear smoother and more youthful but do not significantly reverse photoaging on their own.

If Your Main Goal Is…

Use this table as a quick reference when comparing common anti-aging treatments.

If Your Main Goal Is… Best Choice
Maximum wrinkle reductionTazarotene
Most evidence-based anti-aging treatmentTretinoin
Strong anti-aging without prescriptionRetinaldehyde
Beginner retinoidAdapalene
Brightening dull skinVitamin C
Improving age spotsHydroquinone
Improving melasmaHydroquinone or Cysteamine
Sensitive skin anti-agingNiacinamide
Rosacea and aging skinAzelaic Acid
Hydration and plumpingHyaluronic Acid
Barrier repairCeramides
Complete anti-aging routineRetinoid + Vitamin C + Niacinamide + Sunscreen

Quick Decision Guide

Not sure which ingredient best matches your skin concerns? This quick guide can help point you in the right direction.

If Your Main Goal Is…Consider
WrinklesTretinoin, Tazarotene
Age SpotsHydroquinone
MelasmaHydroquinone, Cysteamine
Sensitive SkinNiacinamide, Azelaic Acid
Dry SkinHyaluronic Acid, Ceramides
Beginner RetinoidAdapalene
Strongest Non-Prescription RetinoidRetinaldehyde

A practical evidence-based ranking for overall anti-aging effectiveness would be:

Tazarotene → Tretinoin → Retinaldehyde → Vitamin C → Adapalene → Niacinamide ≈ Azelaic Acid → Hydroquinone ≈ Cysteamine → Hyaluronic Acid → Ceramides

Procedures

Some patients may benefit from cosmetic or dermatologic procedures, including:

  • Chemical peels
  • Microneedling
  • Laser resurfacing
  • Fractional laser treatments
  • Intense pulsed light (IPL)
  • Radiofrequency microneedling
  • Neuromodulators such as Botox®
  • Dermal fillers
  • Platelet-rich plasma (PRP)
  • Skin tightening procedures

Procedures are often used when topical treatments are not enough for deeper wrinkles, significant sun damage, scars, or skin laxity.

What Should I Expect To Do To Manage Aging Skin?

Managing aging skin usually requires a long-term routine. Most patients benefit from daily prevention, consistent topical treatment, and periodic follow-up.

Labs

Most patients with aging skin do not need routine lab testing unless there is concern for another medical condition.

Thyroid Function Tests

What It Measures

Thyroid hormone levels

What Results Mean

Abnormal thyroid levels can contribute to dry, thin, or fragile skin

How Often

Only if symptoms suggest thyroid disease

Vitamin D Level

What It Measures

Vitamin D status

What Results Mean

Low vitamin D may occur in patients avoiding sun exposure, though sunscreen use alone usually does not require testing

How Often

Only if clinically indicated

Iron Studies / CBC

What It Measures

Anemia or iron deficiency

What Results Mean

May be checked if there is hair loss, fatigue, poor healing, or unusual bruising

How Often

Only if clinically indicated

Hormonal Testing

What It Measures

Estrogen, testosterone, or other hormones

What Results Mean

May be considered if skin changes occur with menopause, PCOS, or other hormonal symptoms

How Often

Only if clinically indicated

Diagnostics

Aging skin is usually diagnosed by clinical examination.

Skin Examination

What It Measures

Texture, wrinkles, pigmentation, thinning, bruising, sun damage

What Results Mean

Helps determine severity of aging skin and whether lesions need further evaluation

How Often

At routine visits or annually if significant sun damage

Full-Body Skin Check

What It Measures

Screens for precancerous spots and skin cancers

What Results Mean

Important because sun damage that ages skin also increases skin cancer risk

How Often

Often yearly for higher-risk patients

Dermoscopy

What It Measures

Magnified evaluation of skin lesions

What Results Mean

Helps distinguish benign sun spots from concerning lesions

How Often

As needed

Skin Biopsy

What It Measures

Microscopic evaluation of a suspicious spot

What Results Mean

Used if a lesion may be precancerous or cancerous

How Often

As needed

Referrals

Who Manages Aging Skin?

A Primary Care Provider may help identify general skin concerns, screen for medical causes of fragile skin, review medications, and refer when needed.

However, aging skin, photoaging, precancerous lesions, and cosmetic treatment planning are more commonly managed by a dermatologist, also called a skin doctor.

A dermatologist can:

  • Diagnose the type and severity of photoaging
  • Identify precancerous or cancerous lesions
  • Prescribe topical retinoids
  • Recommend pigmentation treatments
  • Perform cosmetic procedures
  • Treat fragile, bruising, or thinning skin
  • Create a long-term skin maintenance plan

Your PCP may handle some aspects of aging skin, but more commonly a specialist in dermatology manages this condition. It is common for your PCP to refer you to a dermatologist who can make a formal and accurate diagnosis of the specific type and severity of your skin condition. Sometimes, your PCP can continue a treatment regimen your dermatologist has started. Other times, your condition may be more complex, advanced, or cosmetic-procedure focused and requires the dermatologist to continue your care.

Is Aging Skin Curable?

Aging skin is not “curable” because aging is a normal lifelong process. However, many signs of aging skin can be improved, slowed, or partially reversed, especially when they are caused by sun damage.

Topical retinoids, sunscreen, antioxidants, moisturizers, and dermatologic procedures can improve:

  • Fine lines
  • Texture
  • Brown spots
  • Roughness
  • Uneven tone
  • Early wrinkles

Deeper wrinkles, sagging skin, and significant volume loss may require procedures for best results.

How Can I Help My Aging Skin?

You can help aging skin by focusing on prevention and consistency.

Most helpful steps include:

  • Wear sunscreen every day
  • Avoid tanning beds
  • Start a retinoid if appropriate
  • Use moisturizer daily
  • Avoid smoking
  • Avoid picking or aggressively exfoliating the skin
  • Use vitamin C or niacinamide if tolerated
  • Get suspicious spots checked
  • Be patient: topical treatments often take 3–6 months to show meaningful improvement
  • Continue treatment long-term to maintain results

The most important anti-aging product is daily sunscreen, and the most evidence-based prescription anti-aging treatments are topical retinoids.

Anti-Aging Treatment FAQs

How do retinoids help with aging skin?

Retinoids encourage skin renewal and support collagen production, which can improve skin texture, reduce the appearance of fine lines, and help fade sun damage and discoloration over time. Because these improvements occur gradually, consistent use over several months is usually needed to achieve the best results.


How long until I see results?

Anti-aging treatments require patience. Some people notice smoother skin within a few weeks, but visible improvements in fine lines, wrinkles, skin texture, and pigmentation often take 3–6 months or longer with consistent use. Continuing treatment and protecting your skin from the sun are important for maintaining results.


Is peeling and irritation normal?

Yes. Mild redness, dryness, flaking, and peeling are common when starting a retinoid. This adjustment period, sometimes called retinization, usually improves as your skin becomes accustomed to treatment. Using a gentle moisturizer, introducing the medication gradually, and following your provider’s instructions can help reduce irritation.


Do I need sunscreen while using a retinoid?

Yes. Daily use of a broad-spectrum sunscreen with SPF 30 or higher is strongly recommended. Retinoids can make your skin more sensitive to sunlight, and protecting your skin from UV exposure helps preserve the benefits of treatment while reducing additional sun damage and premature aging.


Can people with sensitive skin use retinoids?

Often, yes. Many people with sensitive skin can successfully use retinoids by starting with less frequent applications, using a moisturizer to support the skin barrier, and gradually increasing use as tolerated. Your healthcare provider can recommend a treatment plan that matches your skin type and goals.

Where Can I Get More Information About Aging Skin?

Trusted resources include:

American Academy of Dermatology

https://www.aad.org

Skin Cancer Foundation

https://www.niams.nih.gov

National Institutes of Health

https://www.nih.gov

MedlinePlus

https://medlineplus.gov

Mayo Clinic

https://www.mayoclinic.org

Cleveland Clinic

https://my.clevelandclinic.org

American Society for Dermatologic Surgery

https://www.asds.net

American Society for Laser Medicine and Surgery

https://www.aslms.org

Ready to build a personalized anti-aging plan?

Every person’s skin ages differently. During your telehealth consultation, an APNS provider will evaluate your skin concerns, discuss your goals, and recommend evidence-based treatment options tailored to your needs. Get started today with convenient, affordable care from wherever you are.