Launching January 2027

Fever

Fever At A Glance

  • 100.4°F (38°C) or higher is commonly considered a fever in adults.
  • Infections are the most common cause, including viral and bacterial illnesses.
  • Common symptoms include chills, sweating, headache, body aches, fatigue, thirst, and reduced appetite.
  • Treatment depends on the cause and may include rest, fluids, fever-reducing medication, or treatment of an underlying infection or illness.
  • The temperature alone does not determine severity—breathing problems, confusion, dehydration, severe pain, rash, and other symptoms can be more important warning signs.

Table of Contents

Table of Contents

What Is Fever?

A fever is a temporary rise in body temperature, usually because the immune system is responding to an infection or another illness. Normal temperature varies by person, time of day, activity, and measurement method. In adults, a measured temperature of 100.4°F (38°C) or higher is commonly considered a fever.

Fever is a symptom, not a diagnosis. The temperature number alone does not show how serious an illness is; breathing, alertness, hydration, pain, rash, immune status, pregnancy, recent procedures, and other symptoms matter. Heatstroke is different from fever and is an emergency caused by the body overheating rather than resetting its internal temperature in response to illness.

Learn More

Fever – NIH MedlinePlus

https://medlineplus.gov/fever.html

Provides an easy-to-understand overview of fever, common causes, diagnosis, and treatment.

Fever – NIH MedlinePlus Medical Encyclopedia

https://medlineplus.gov/ency/article/003090.htm

Explains fever symptoms, home care, medicines, and reasons to contact a healthcare provider.

How Common Is Fever?

Fever is one of the most common signs of infection and can occur at any adult age. Most short-lived fevers are related to viral illnesses and improve as the illness resolves.

Some adults may have a serious infection without a high fever, especially older adults, people with weakened immune systems, and those taking fever-reducing medicines. A new fever in these groups deserves earlier medical guidance.

What Symptoms Might You Notice?

Symptoms may include:

  • Feeling hot, cold, or chilled
  • Sweating
  • Headache or body aches
  • Tiredness or weakness
  • Reduced appetite
  • Faster heart rate or breathing
  • Thirst, dry mouth, or darker urine
  • Trouble sleeping
  • Symptoms related to the cause, such as cough, sore throat, painful urination, vomiting, diarrhea, rash, or localized pain

A high temperature may be absent even with serious illness. Pay attention to how you feel and whether symptoms are worsening.

Learn More

Fever – NIH MedlinePlus Medical Encyclopedia

https://medlineplus.gov/ency/article/003090.htm

Explains fever symptoms, home care, medicines, and reasons to contact a healthcare provider.

How Is Fever Diagnosed?

A provider will confirm the temperature and ask when it began, how it was measured, what medicines you took, and which symptoms or exposures occurred. They may ask about travel, sick contacts, sexual history, animal or insect exposure, immune conditions, recent surgery, devices, and medications.

The examination may include the ears, throat, lungs, heart, abdomen, skin, joints, nervous system, and urinary or genital areas when relevant. Testing is based on the suspected cause rather than the fever alone.

Learn More

Fever – NIH MedlinePlus

https://medlineplus.gov/fever.html

Provides an easy-to-understand overview of fever, common causes, diagnosis, and treatment.

Fever infographic – click to enlarge

What Causes Fever?

Infection is the most common cause, but fever has many possible explanations.

Causes may include:

  • Respiratory viruses, influenza, COVID-19, or other viral infections
  • Urinary, skin, dental, abdominal, lung, or bloodstream bacterial infections
  • Fungal or parasitic infections, especially after travel or with immune suppression
  • Inflammatory or autoimmune conditions
  • Certain cancers
  • Blood clots or tissue injury
  • Medication reactions
  • Recent vaccination
  • Surgery or other procedures
  • Thyroid storm or other uncommon medical emergencies

Overheating from hot weather, strenuous activity, or certain drugs is hyperthermia rather than a true fever and requires urgent cooling and medical evaluation when severe.

What Can Make Fever Worse?

Dehydration, heavy blankets, strenuous activity, and a hot environment can increase discomfort and strain on the body.

Risk of complications is higher with:

  • A weakened immune system
  • Cancer treatment, transplant medicines, or long-term high-dose steroids
  • Pregnancy
  • Advanced age or frailty
  • Heart, lung, kidney, liver, or neurologic disease
  • Recent surgery, hospitalization, implanted device, or catheter
  • Travel, animal or tick exposure, or known infectious exposure
  • Inability to keep fluids down
  • Delaying evaluation despite severe or worsening symptoms

Prevention

Not every fever can be prevented, but many infections and heat-related illnesses can be reduced.

  • Stay current with recommended vaccinations.
  • Wash hands and improve indoor air when respiratory illness is spreading.
  • Avoid close contact or share fewer items when someone is contagious.
  • Use safe food handling and clean drinking water.
  • Practice safer sex and do not share needles.
  • Use insect repellent and check for ticks when appropriate.
  • Care for wounds and medical devices as instructed.
  • Stay hydrated and avoid strenuous heat exposure during extreme temperatures.

Learn More

Vaccines and Immunizations – Centers for Disease Control and Prevention

https://www.cdc.gov/vaccines-adults/index.html

Provides adult vaccination recommendations that help prevent several fever-causing infections.

Preventing Respiratory Illnesses – Centers for Disease Control and Prevention

https://www.cdc.gov/respiratory-viruses/prevention/index.html

Reviews practical steps that reduce the spread of respiratory infections.

Labs

Many mild, short-lived fevers do not require laboratory testing. Tests are selected according to symptoms, duration, risk factors, and examination findings.

Possible tests include:

  • Complete Blood Count: Looks for changes that may occur with infection, inflammation, anemia, or immune problems.
  • Metabolic Panel: Evaluates hydration, electrolytes, kidney function, liver function, and glucose.
  • Urinalysis and Urine Culture: Check for urinary infection.
  • Respiratory Testing: May test for influenza, COVID-19, or other viruses when results affect care.
  • Blood Cultures: Used when bloodstream infection or sepsis is suspected, ideally before antibiotics when this does not delay care.
  • Other Cultures or Targeted Tests: May involve sputum, stool, wounds, sexually transmitted infections, tick-borne illness, HIV, hepatitis, or travel-related infections.

Diagnostics

Imaging and procedures are used only when symptoms or examination suggest a specific source.

  • Chest X-Ray: Looks for pneumonia or another lung problem.
  • Ultrasound or CT Scan: May evaluate abdominal pain, kidney infection, abscess, gallbladder disease, appendicitis, or another source.
  • Lumbar Puncture: Tests spinal fluid when meningitis or encephalitis is suspected.
  • Echocardiogram: May be used when a heart-valve infection is suspected.
  • Biopsy or Specialized Imaging: Sometimes needed for prolonged unexplained fever, inflammatory disease, or cancer concerns.

Treatment & Management

Treatment Options

Treatment depends on the cause, severity, and your health risks. A mild fever does not always need to be lowered if you are comfortable and able to drink fluids.

Treatment may include:

  • Rest and fluids
  • Acetaminophen or an NSAID when medically safe
  • Antiviral medicine for selected infections when started within the recommended time
  • Antibiotics only for confirmed or strongly suspected bacterial infection
  • Treatment of inflammation, medication reaction, blood clot, or another noninfectious cause
  • Intravenous fluids, oxygen, drainage of an abscess, or hospital care for severe illness
  • Emergency cooling for heatstroke

Antibiotics do not treat viral infections and should not be saved, shared, or taken without a prescription.

Lifestyle Changes

Lifestyle Changes

While recovering, reduce physical activity and prioritize rest. Drink fluids regularly unless a clinician has placed you on fluid restriction.

  • Wear light, comfortable clothing.
  • Keep the room comfortably cool.
  • Avoid heavy blankets once chills pass.
  • Choose water, broth, or oral rehydration fluids when appropriate.
  • Avoid alcohol and strenuous exercise.
  • Eat as tolerated without forcing food.
  • Stay home and limit close contact when you may be contagious.
  • Follow infection-specific masking and isolation guidance.

Medications

Fever-reducing medicine is mainly used for comfort. Read every label and ask a pharmacist when you have medical conditions, take blood thinners, are pregnant, or use multiple cold and flu products.

  • Acetaminophen (Tylenol®): Reduces fever and aches. Do not take more than the package or prescription allows, and do not combine multiple acetaminophen-containing products. Ask before use with liver disease or heavy alcohol use.
  • Ibuprofen (Advil®, Motrin®) or Naproxen (Aleve®): NSAIDs reduce fever and pain but may cause stomach bleeding, kidney injury, fluid retention, or cardiovascular problems. Ask before use with kidney disease, ulcers, blood thinners, heart disease, dehydration, or pregnancy.
  • Prescription Antimicrobials: Antibiotics, antivirals, antifungals, or antiparasitic medicines are used only when the likely cause calls for them.

Do not alternate medicines or exceed label doses unless a healthcare professional gives you a clear schedule. FDA recommends avoiding NSAIDs at 20 weeks of pregnancy or later unless specifically advised.

Learn More

Acetaminophen Safety – U.S. Food and Drug Administration

https://www.fda.gov/drugs/safe-use-over-counter-pain-relievers-and-fever-reducers/acetaminophen

Explains how to avoid accidental overdose and use acetaminophen-containing products safely.

Safe Use of Over-the-Counter Pain Relievers and Fever Reducers – FDA

https://www.fda.gov/drugs/understanding-over-counter-medicines/safe-use-over-counter-pain-relievers-and-fever-reducers

Provides safety information for acetaminophen and nonsteroidal anti-inflammatory drugs.

Procedures

Fever itself usually does not require a procedure. A procedure may be needed to diagnose or treat the cause.

  • Abscess Drainage: Removes infected fluid that antibiotics may not clear by themselves.
  • Removal or Exchange of an Infected Device: May involve a catheter, intravenous line, or implanted device.
  • Lumbar Puncture: Collects spinal fluid when meningitis is suspected.
  • Surgery: May be required for appendicitis, infected gallbladder, bowel perforation, severe tissue infection, or another surgical source.

Severe infection may require hospital monitoring, intravenous medicine, oxygen, or intensive care.

What Should You Expect Long-Term?

Most fevers caused by routine viral infections improve within several days. The temperature may rise and fall, and tiredness or cough may continue after the fever resolves.

Fever that persists, repeatedly returns, or has no clear cause needs medical evaluation. Long-term expectations depend on the underlying infection, inflammatory disease, medication reaction, or other diagnosis.

What Can You Do At Home?

Use a digital thermometer and record the number, time, measurement location, symptoms, and medicines taken. Oral, ear, forehead, and underarm methods can give different readings, so use the same method when tracking trends when possible.

  • Rest and drink fluids regularly.
  • Take fever medicine only as directed and mainly for comfort.
  • Wear light clothing and use a light blanket if chilled.
  • Use lukewarm water for comfort if desired.
  • Do not use ice baths or alcohol rubs because they can cause shivering or toxicity.
  • Monitor urine output, breathing, alertness, rash, pain, and ability to drink.
  • Follow testing and infection-control guidance for the suspected illness.

Learn More

Body Temperature Norms – NIH MedlinePlus

https://medlineplus.gov/ency/article/001982.htm

Explains normal temperature variation and common measurement methods.

Frequently Asked Questions

Is 100.4°F a fever?

Yes. In adults, 100.4°F (38°C) or higher is commonly used as a fever threshold, though the measurement method and your baseline temperature matter.

Do I need medicine every time I have a fever?

No. Fever medicine is mainly for comfort. The underlying symptoms, risks, hydration, and cause are more important than making the temperature perfectly normal.

Does a higher fever always mean a worse infection?

No. Some mild illnesses cause high fever, and serious infections may cause only a small temperature rise or none at all.

Should I use antibiotics for fever?

Only when a clinician diagnoses or strongly suspects a bacterial infection. Antibiotics do not treat viruses.

Can I take acetaminophen with cold medicine?

Check the active ingredients first. Many cold and flu products already contain acetaminophen, and combining them can cause an overdose.

Is heatstroke the same as fever?

No. Heatstroke is dangerous overheating, often with confusion or collapse, and requires emergency cooling and medical care.

Learn More

Heat Emergencies – NIH MedlinePlus

https://medlineplus.gov/ency/article/000056.htm

Explains heat exhaustion and heatstroke, which require different care from infection-related fever.

Questions To Ask Your Provider

Consider asking:

  • What temperature and measurement method should concern me?
  • Which symptoms suggest a serious infection?
  • Do I need testing for influenza, COVID-19, urinary infection, or another cause?
  • Which fever-reducing medicine is safest with my conditions and prescriptions?
  • Could one of my medicines be causing the fever?
  • How much fluid should I drink?
  • When should I return if the fever continues?
  • Am I contagious, and when can I return to work or normal activities?

Specialist Referrals

Most short-term fevers are managed by primary or urgent care. Referral depends on the suspected cause.

  • Primary Care or Urgent Care Provider: Evaluates common infections and arranges initial testing.
  • Infectious Disease Specialist: Assesses prolonged, recurrent, unusual, travel-related, or difficult-to-treat infections.
  • Rheumatologist: Evaluates suspected autoimmune or inflammatory disease.
  • Hematologist or Oncologist: Evaluates certain blood disorders or cancers.
  • Emergency Medicine: Treats severe symptoms, sepsis, meningitis concerns, heatstroke, or unstable vital signs.

Is Fever Curable?

Fever is a symptom rather than a disease, so whether it resolves depends on the cause. Most infection-related fevers stop when the immune system clears the illness or the underlying infection is treated.

Reducing the temperature does not cure the cause. Recurrent or prolonged fever may require targeted treatment for an infection, inflammatory condition, medicine reaction, or another illness.

Emergency Symptoms / When To Seek Immediate Help

Call 911 or seek emergency care for fever with signs of severe illness, even if the temperature is not extremely high.

  • Difficulty breathing, blue lips, severe chest pain, or oxygen levels that are dangerously low
  • Confusion, inability to awaken normally, fainting, new weakness, or seizure
  • Severe headache with stiff neck, light sensitivity, or a purple or nonblanching rash
  • Signs of sepsis, such as rapid breathing, severe weakness, clammy skin, confusion, very low urine output, or feeling that something is seriously wrong
  • Severe abdominal pain, repeated vomiting, or inability to keep fluids down
  • Temperature around 105°F (40.6°C) or higher
  • Overheating with confusion, collapse, hot skin, or neurologic symptoms
  • Fever during profound immune suppression or soon after chemotherapy, transplant, or another high-risk treatment as directed by the care team

Contact a provider promptly for fever lasting more than several days, repeated fever, new fever after surgery, fever with painful urination or worsening localized pain, or any fever when your clinician has given you a lower threshold for seeking care.

Learn More

Sepsis – NIH MedlinePlus

https://medlineplus.gov/sepsis.html

Reviews warning signs of a life-threatening response to infection and the need for rapid treatment.

CALL 911

APNS does not provide emergency medical services. If you believe you are experiencing a medical emergency, including (but not limited to) chest pain, difficulty breathing, stroke symptoms, severe allergic reactions, anaphylaxis, uncontrolled bleeding, seizures, loss of consciousness, or any other potentially life-threatening condition, you are instructed to call 911 immediately or go immediately to the nearest emergency department.

Official Resources / External Links

Fever – NIH MedlinePlus

https://medlineplus.gov/fever.html

Provides an easy-to-understand overview of fever, common causes, diagnosis, and treatment.

Fever – NIH MedlinePlus Medical Encyclopedia

https://medlineplus.gov/ency/article/003090.htm

Explains fever symptoms, home care, medicines, and reasons to contact a healthcare provider.

Acetaminophen Safety – U.S. Food and Drug Administration

https://www.fda.gov/drugs/safe-use-over-counter-pain-relievers-and-fever-reducers/acetaminophen

Explains how to avoid accidental overdose and use acetaminophen-containing products safely.

Safe Use of Over-the-Counter Pain Relievers and Fever Reducers – FDA

https://www.fda.gov/drugs/understanding-over-counter-medicines/safe-use-over-counter-pain-relievers-and-fever-reducers

Provides safety information for acetaminophen and nonsteroidal anti-inflammatory drugs.

NSAID Use During Pregnancy – U.S. Food and Drug Administration

https://www.fda.gov/drugs/drug-safety-and-availability/fda-recommends-avoiding-use-nsaids-pregnancy-20-weeks-or-later-because-they-can-result-low-amniotic

Explains why NSAIDs should generally be avoided at 20 weeks of pregnancy or later unless specifically advised.

Sepsis – NIH MedlinePlus

https://medlineplus.gov/sepsis.html

Reviews warning signs of a life-threatening response to infection and the need for rapid treatment.

Body Temperature Norms – NIH MedlinePlus

https://medlineplus.gov/ency/article/001982.htm

Explains normal temperature variation and common measurement methods.

Heat Emergencies – NIH MedlinePlus

https://medlineplus.gov/ency/article/000056.htm

Explains heat exhaustion and heatstroke, which require different care from infection-related fever.

Vaccines and Immunizations – Centers for Disease Control and Prevention

https://www.cdc.gov/vaccines-adults/index.html

Provides adult vaccination recommendations that help prevent several fever-causing infections.

Preventing Respiratory Illnesses – Centers for Disease Control and Prevention

https://www.cdc.gov/respiratory-viruses/prevention/index.html

Reviews practical steps that reduce the spread of respiratory infections.

This guide is intended for educational purposes only and should not replace medical advice, diagnosis, or treatment from your healthcare provider. Fever can result from infection, inflammation, a medicine reaction, cancer, heat illness, or another condition requiring different treatment. Temperature alone does not determine severity. Use over-the-counter fever medicines only as directed, avoid combining acetaminophen-containing products, and ask before using NSAIDs if you have kidney disease, ulcers, bleeding risk, heart disease, dehydration, or pregnancy. Seek emergency care for breathing difficulty, confusion, seizure, stiff neck with severe headache, a concerning rash, signs of sepsis, severe dehydration, heatstroke symptoms, or other rapidly worsening illness.

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